• Engineered to allow young patients to return to active life styles following meniscus injury
  • Designed to restore mobility following degenerative tears
  • Entirely anatomical total meniscus replacement
  • Revolutionising orthopaedics and the treatment for meniscus injury

Orthonika is a spin-out company from Imperial College London developing the Total Meniscus Replacement, a unique entirely anatomical replacement for the meniscus of the knee

Meniscus Injury

Meniscus injury can be severely debilitating and may lead to osteoarthritis and the need for knee arthroplasty. Today’s treatment options are very limited resulting in a high unmet need. Partial meniscectomy does not restore full joint biomechanics and is thought to lead to knee osteoarthritis1 2. Partial replacement is only suitable as long as the meniscal rim is intact. Allograft transplantation has severe limitations including donor availability, risk of infection and sizing and is associated with high morbidity and socioeconomic costs.

Man holding knee

Our Innovation

We are developing the Total Meniscus Replacement the first entirely anatomical replacement for the meniscus of the knee. It is being engineered using a unique material structure which replicates the structure function relationship of the natural tissue. The innovative structure uses a novel fibre reinforced structure embedded in a proprietary polymer. The implant is currently in development at the pre-clinical stage.

News & Media

9th January 2017
Orthonika is invited to attend the JP Morgan Healthcare conference; Co-Founder Mario Alberto Accardi will be attending the event
4th May 2016
Professor Andrew Amis and Dr Camilla Halewood present "Early development of a meniscus prosthesis" at the instructional course on "New Horizons in Meniscus Replacement"


  1. Roos et al.1998. Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis & Rheumatology, Apr;41(4), pp. 687-93.
  2. Rangger et al. 1995. Osteoarthritis after arthroscopic partial meniscectomy. American Journal of Sports Medicine, 23 (2), pp. 240–244